How to Interpret a Paternity
Test Report
Make sure the laboratory you choose is listed on
the A.A.B.B. web site
CLICK HERE TO SEE A COMPLETE LIST Of WHO'S
REALLY A.A.B.B. ACCREDITED
"
We are Listed as SWBIC
Genetic Testing Laboratory New Mexico State University "
Click
Here for an Example Paternity Test Report,
which will, for your convenience, open in a new browser window.
The
Paternity Test
Report shows the results of laboratory tests that provide evidence
regarding the alleged family relationship. This is a brief explanation
of the meaning of the numbers and other items that appear in a paternity
test report.
The
laboratory tests the DNA isolated from buccal (cheek) swabs to locate
certain regions of chromosomes that vary in length between individuals.
Sixteen of these sites are tested, each site is called a "locus”,
(“loci” – plural). Analysis of these 16 loci in a large population has
revealed many different sized fragments, or alleles, associated with
each locus. These are the genetic markers* used in parentage analysis.
Because
each individual has two of each type of chromosome, one inherited from
each parent, everyone has two alleles at each locus. These two alleles
are sometimes identical (homozygous), but usually they are not the same
size (heterozygous). During parentage testing, the laboratory identifies
the length of the two alleles found at each locus. The report you will
be given shows numbers (in the first column) that indicate each of the
16 loci involved in the testing process.
The
columns marked “allele” on the report contain numbers indicating the two
alleles found at each locus (or one number if they are the same size).
If, for
example, a child has two alleles that are designated 12.1 and 18, and if
the mother has alleles 12.1 and 16, then the child inherited the 12.1
allele from the mother. The child has to have inherited the 18 allele
from the father. The 18 allele is the "obligate paternal allele."
Generally, the alleged father must have this allele if he is the
biological father of the child.
Fifteen
different loci are used as genetic markers in the tests, as well as one
(Amelogenin) to confirm the sex of the person providing the sample. If
the alleged father does not have the matching allele at every tested
locus, then he usually cannot be the biological parent. If he does have
it, then he could be the father. A "relationship index" (called the
“Direct Index” in the report) for each locus is calculated based on
information including the portion of the male population that has the
obligate paternal allele at that locus. This index is reported for each
DNA locus.
A
combined relationship (or “Direct”) index for all of the tested alleles
is then calculated and appears below the chart. This number is used to
calculate the "probability of relationship,” which is the percentage
likelihood that a man with the alleles of the alleged father is the
biological parent of the child, as compared to an untested, unrelated
man of the same race. If the DNA of the alleged father is consistent (to
a degree of mathematical certainty) with that of the child, then the
report will conclude that the alleged father cannot be excluded as the
biological father of the child. If the DNA is not consistent, it will
conclude that the alleged father can be excluded as the biological
father of the child.
* Each
locus used in the testing is composed of a variable number of repeating
short sequences of the bases A,C,T, and G; such as ACGACGACGACG. Each
allele has a different number of repeats giving rise to a different
fragment length amplified by the polymerase chain reaction (PCR).
Please Call Us @ (877) 786-9543 Or
E-mail US:
Sales@paternityusa.com
A
Case Manager Is Standing By To Answer Your
Questions, And Take Your Order.
 |